Low Intensity Pulsed Ultrasound Versus High Intensity Continuous Ultrasound Therapy in Knee Osteoarthritis

Ministry of Health and Sports, Myanmar86 enrolled

Overview

To compare the effects of low intensity pulsed ultrasound with high intensity continuous ultrasound in knee osteoarthritis

Knee osteoarthritis is a common disorder affecting elderly and obese. Currently, there are 3 types of treatment; pharmacological, non-pharmacological and surgery. Though ultrasound, a non-pharmacological treatment, is increasingly used in knee osteoarthritis, the advantages and disadvantages of low intensity pulsed ultrasound (LIPUS) and high intensity continuous ultrasound (HICUS) are yet to be clarified. Therefore, a randomized control trial will be done to compare LIPUS and HICUS in participants with knee osteoarthritis presenting to Department of Physical Medicine and Rehabilitation, Yangon General Hospital, Myanmar.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

Osteoarthritis, Knee Osteoarthritis Rheumatic Diseases Musculoskeletal Diseases

Interventions

Low intensity pulsed ultrasoundDEVICE

Low intensity pulsed ultrasound therapy will use ultrasound with frequency of 1.5 MHz, power intensity of 30 mW/cm\^2 (0.03 W/cm\^2 ) and 20% duty cycle.

High intensity continuous ultrasoundDEVICE

High intensity continuous ultrasound therapy will use ultrasound with frequency of 1 MHz, power intensity of 3 W/cm\^2 and 100% duty cycle.

Eligibility

Sex: ALLMin age: 40 YearsMax age: 70 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Participants with knee pain (VAS 3 to 6) * Kellgren and Lawrence grade 2 and 3 in X' ray knee joint Exclusion Criteria: * Rheumatoid arthritis, Gouty arthritis, Spondyloarthropathies, Metabolic arthropathies * Infection of knee joint * Tumor of knee joint * History of hypersensitivity to heat * Previous knee surgery in affected side * Intra-articular injection within previous 3 months * Participants taking treatment with other physical modalities such as low-level laser therapy and Trans Cutaneous Electrical Nerve Stimulation

Locations (1)

Department of Physical Medicine and Rehabilitation, Yangon General Hospital

Yangon, Burma

RECRUITING

Outcomes

Primary Outcomes

Visual Analog Scale (VAS)

It is one of the most commonly used measures of pain intensity and it is divided into 10 ordinal ratings with 0 being "no pain" and 10 being "pain as bad as it could be".

Time frame: 8 weeks

Western Ontario McMaster University Osteoarthritis Index Inventory (WOMAC)

This index measures clinically important symptoms of pain, stiffness and function. It consists of 23 questions (5 pain, 2 stiffness and 16 physical function) and the maximum score is 100, indicating the worst outcome while the minimum score is 0, indicating the best outcome.

Time frame: 8 weeks

Percentage of participants with skin irritation

Skin irritation, a possible complication of ultrasound therapy, will be recorded as a dichotomous variable (i.e. present or absent).

Time frame: 8 weeks

Percentage of participants with tingling

Tingling sensation, a possible complication of ultrasound therapy, will be recorded as a dichotomous variable (i.e. present or absent).

Time frame: 8 weeks

Percentage of participants with oedema

Oedema, a possible complication of ultrasound therapy, will be recorded as a dichotomous variable (i.e. present or absent).

Time frame: 8 weeks

Percentage of participants with burns

Burns, a possible complication of ultrasound therapy, will be recorded as a dichotomous variable (i.e. present or absent).

Time frame: 8 weeks

Central Contacts

Wunn Lei Thwe, M.B.,B.S

CONTACT

+959786478599 wunnleithwe92@gmail.com

Data from ClinicalTrials.gov

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