The aim of this randomized controlled trial is to determine whether co-administration of GnRH agonist and hCG for final oocyte maturation ( 40 and 34 h prior to oocyte retrieval , respectively) can increase the oocytes yield in patients with history of poor oocytes yield, despite normal response to COH, due to low (\<50%) number of oocytes retrieved per number of follicles \> 14 mm in diameter on day of hCG administration
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
56
Final follicular maturation is triggered by the co-administration of GnRH-agonist (Triptorelin acetate, decapeptyl 0.2 mg, Slough, United Kingdom) and 10000 IU of HCG, 40 and 34 h prior to oocyte retrieval, respectively
Final follicular maturation is triggered by a dose of 10000 IU of HCG 36 h prior to oocyte retrieval
Riyadh Fertility and Reproductive Health center
Giza, Egypt
RECRUITINGNumber of oocytes retrieved
Time frame: First day after oocyte retrieval
clinical pregnancy rate
The presence of gestational sac detected by ultrasound examination
Time frame: First 5 weeks after oocyte retrieval
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