A Study to Measure Stomach Emptying in Overweight Non-diabetic and Diabetic Participants Using Tirzepatide

Inclusion Criteria: * Have a body mass index (BMI) between 27 to 45 kilograms per meter squared (kg/m²), inclusive at screening * For nondiabetic subjects: as determined by medical history, physical examination, and safety assessments at screening * For participants with a confirmed type 2 diabetes diagnosis: The condition must be managed either by diet and exercise alone or on a stable dose of metformin for the past 3 months * Willing and agreeable to commit to the duration of the study and undergo study procedures as instructed by the clinic staff Key Exclusion Criteria * Have undergone gastric bypass or bariatric surgery * Have received prescription drugs or over the counter drugs that promote weight loss in the past 6 months prior to screening * For participants with a confirmed type 2 diabetes diagnosis: Have experienced more than 1 episode of severe low blood sugar that require emergency treatment, hospitalization or third parties to administer rescue treatment, in the past 6 months * Have any lifetime history of a suicide attempt * Have other medical conditions or medical history that make participation in the study unsafe or which may interfere in the interpretation of the results of the study * Unwilling to comply with smoking and alcohol restrictions during the study