Effects of Tolperisone on Measures of Drowsiness and Cognitive Function

Inclusion Criteria: * Ambulatory male or female, between 21 and 65 years of age, inclusive, for the entire duration of the study (from Screening through Day 3 of last treatment period). * Body mass index (BMI) range between 18.5 and 30.0 kg/m2, inclusive. * Subject must possess a valid driver's license and be an active driver and have driven a minimum of 10,000 miles (about 16,000 km) per year for the previous 3 years. * Subject must demonstrate simulator sickness questionnaire scores that are not indicative of simulator sickness as defined in the driving simulation operations manual. * Subject must have a regular sleep pattern, not be engaged in shift-work, and in general, have at least 7 hours of sleep each night. Exclusion Criteria: * History of sleep disorders, including insomnia, sleep apnea, Restless Legs Syndrome (RLS), or narcolepsy, night-shift workers, routine daytime napping or oversleeping on weekends days (off work) or a score higher than 10 on the Epworth Sleepiness Scale (ESS) at Screening. * A history of difficulty in falling asleep or staying asleep in the previous 3 months that is considered clinically significant by the Investigator. * Subject has traveled across 2 or more time zones (trans meridian travel) in the last 2 weeks prior to randomization or is expected to travel across 2 or more time zones during the study. * Subject has any physical condition (e.g., severe vision issues, hand use limitations) that would prevent the subject from performing the cognitive or drowsiness assessments. * Subject has a presence or history of any medically diagnosed, clinically significant psychiatric disorder, including depression, anxiety, insomnia, schizophrenia, or bipolar disorder. * Consumes more than 3 cups of coffee per day. * Female subjects who are pregnant or lactating. * Any clinically significant medical abnormality, any clinically significant chronic disease, or any clinically significant finding on physical examination. * Subject with a genotype status of poor-, ultrarapid-, or indeterminate- metabolizers of cytochrome CYP2D6. * Subject is unable to remain in the research unit for each of the treatment periods. * Subject has visual or auditory impairment which in the opinion of the Investigator would interfere with study related procedures or study conduct.