Diagnostic Value of Patient - Reported and Clinically Verified Olfactory Disorders (COVID-19)

University Hospital, Montpellier809 enrolled

Overview

Participants are healthcare workers and adult outpatients referred in a COVID-19 screening center. Patients-reported symptoms are collected, then participants underwent a simple olfactory test (CODA for Clinical Olfactory Dysfunction Assessment), prior to swabbing for SARS-CoV-2 diagnosis (RT-PCR). We aimed to evaluate the prevalence of smell and taste disorders, and to calculate the diagnostic value of patient-reported and clinically verified smell disorders in persons with suspected COVID-19.

Study Type

OBSERVATIONAL

Enrollment

809

Conditions

COVID-19

Interventions

Reporting of anosmia, ageusia and other clinical symptomsBIOLOGICAL

Reporting of anosmia, ageusia and other clinical symptoms related to COVID-19 - CODA test - SARS-CoV2 RT-PCR and ELISA

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion criteria: * Symptoms compatible with COVID-19 * Close exposure to a confirmed COVID-19 index case * Ambulatory (asymptomatic, or if symptomatic, did not require hospitalisation, thus with initial mild disease) Exclusion criteria: * known history of smell and taste disorders * testing inability (cognitive impairment, non native French speakers, test malingering) * testing contraindication (children, pregnancy, breastfeeding, specific allergies).

Locations (1)

Uhmontpellier

Montpellier, France

Outcomes

Primary Outcomes

Diagnostic values of anosmia and ageusia for COVID-19

Diagnostic values of anosmia and ageusia for COVID-19 with questionnaire

Time frame: at inclusion

Secondary Outcomes

Diagnostic values of CODA

Diagnostic values of CODA (Clinical Olfactory dysfunction Assessment) score for COVID-19 : Simple, fast, semi-objective olfactory test developed for epidemic context

Time frame: at inclusion

Data from ClinicalTrials.gov

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