Use of Convalescent Plasma for COVID-19

Inclusion Criteria: * Documented COVID-19 infection by nasal pharyngeal sampling * COVID-19 disease falling into one of the following groups: * Critical disease: respiratory failure requiring mechanical ventilation, pressor support, or multiple organ dysfunction/failure * Severe disease: tachypnea \>/=30 per min, O2 sats \</=93% at rest, PaO2/FiO2 index \</=300mmHg * High Risk: upper respiratory symptoms but no radiographic evidence of disease, immunocompromised, insulin-dependent diabetes, poorly controlled HIV disease, moderate to severe asthma history, severe COPD, morbid obesity (BMI \>/=40, age \>/=65 years * Health Care Providers: health care providers at risk to exposure to COVID-19 infection or those with mild to non-severe disease Exclusion Criteria: * History of IgA deficiency * History of anaphylatic reaction to blood product transfusion including hypersensitivity to immunoglobulin therapy