The COVIDHELP study will prospectively evaluate the yet unknown clinical course of the COVID-19 infection in cancer patients and document the impact of potential infrastructural limitations on cancer care of COVID-19 positive patients. All patients consenting will provide peripheral blood samples for prospective biobanking with the aim of investigating immune response and immunity against COVID-19.
Based on patients, who are treated in the University Cancer Center Hamburg (UCCH) and its contracted partner network, which comprises all cancer treating departments at the University Medical Center of Hamburg-Eppendorf (UKE), as well as 19 office-based oncologists and 20 surrounding hospitals, recruitment for the study will be done as follows: (i) as a cancer patient during regular aftercare appointments who reports a current or past COVID-19 infection. (ii) as an acute COVID-19 patient who reports a prevalent cancer diagnosis Data will be collected as available from routine clinical care and includes demographic and biometric data, medical history, baseline data at inclusion as well as inpatient and intensive care unit admissions. Upon consent, patients will provide peripheral blood samples at time of inclusion and after 6 month. Recruitment is limited to a one-year period (April 2020 - April 2021).
Study Type
OBSERVATIONAL
Enrollment
500
No Intervention
University Hospital Hamburg Eppendorf
Hamburg, Germany
RECRUITINGRate of hospitalization
Measured in percentage
Time frame: 2 years
Duration of hospitalization
Measured in days from date of admission to definitive discharge
Time frame: 2 years
Rate of admission to intensive care unit
Measured in percentage
Time frame: 2 years
Length of stay in intensive care unit
Measured in days from date of admission to intensive care unit to the date of discharge
Time frame: 2 years
Need of mechanical ventilation
Measured in percentage
Time frame: 2 years
Duration of mechanical ventilation
Measured in days from the date of intubation to the stop date of mechanical ventilation
Time frame: 2 years
Disease-specific mortality rate
COVID-19 associated mortality rate
Time frame: 2 years
Rate of patients, whose oncologic treatment had to be modified due to COVID-19
Measured in percentage. Modification is defined as cancellation, postponement or dose-adjustment of treatment.
Time frame: 2 years
Cellular and humoral immune response to COVID-19 infection
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Analysis of blood samples at time of diagnosis and after 6 month
Time frame: 6 month