Analysis our Embryo transfer data, prospectively collected during the last 6 years (2014- 2019), performed by the same operator YP, who has been doing embryo transfers since 1984. All factors that might impact the embryo transfer will be analyzed. We want to see which factors that influence the success rate are not related to the subjectivity of the operator and could be adjusted through different approaches.
Most patients undergoing IVF or ICSI reach a blastocyst embryo transfer but less achieve pregnancy and live birth. Many reasons have been proposed to explain these results. Among them, the factor Embryo Transfer Procedure gained less of the attention since few papers have been published and most of them had a lot of biases. In order to eliminate possible biases, we wanted to analyze our Embryo transfer data, prospectively collected during the last 6 years (2014- 2019), performed by the same operator YP, who has been doing embryo transfers since 1984. All factors that might impact the embryo transfer will be analyzed. We want to see which factors that influence the success rate are not related to the subjectivity of the operator and could be adjusted through different approaches. Primary outcomes: bhCG positive rate, pregnancy rate, ongoing pregnancy rate, live birth rate. Secondary outcomes: Full bladder, uterine ax orientation, Endometrial thickness, type of catheter, straightforward advancement of the preloaded catheter, use of a stiffer hard catheter to pass through the cervix and the orifice, the site of the uterine cavity that the embryo was released, single or double transfer due to blocked embryo in the catheter. In addition for each embryo transfer variables that may influence the pregnancy rates will be collected: age of the woman, number of oocytes harvested, sperm characteristics, fertilization rate, stage and grade of the embryos the day of transfer
Study Type
OBSERVATIONAL
Enrollment
3,512
undergoing embryo transfer
IAKENTRO Fertility Center
Thessaloniki, Greece
Number of patients with bhCG positive test after embryo transfer
Number of patients bhCG positive up to12 days after embryo transfer
Time frame: Number of patients bhCG positive up to12 days after embryo transfer
Number of patients with on going clinical pregnancy
Number of patients with on going clinical pregnancy up to12 weeks after embryo transfer
Time frame: Number of patients with on going clinical pregnancy up to 12 weeks after embryo transfer
Number of live births after embryo transfer
Number oflive birth up to9 months after embryo transfer
Time frame: Number oflive birth up to 9 months after embryo transfer
Percentage of fullnes of bladder
Percentage of fullness of the bladder during embryo transfer
Time frame: At the time of embryo transfer and the impact of pregnancy test result 12 days after the mebryo transfer
Endometrial thickness
Endometrial thickness prior to embryo transfer
Time frame: prior to embryo transfer
Uterine axe orientation
Uterine axe orientation during embryo transfer
Time frame: At the time of embryo transfer and the impact of pregnancy test result 12 days after the mebryo transfer
Type of embryo transfer catheter
Type of embryo transfer catheter used in the procedure
Time frame: At the time of embryo transfer and the impact of pregnancy test result 12 days after the mebryo transfer
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Distance from the fundus of the embryo release
Distance from the fundus of the embryo release
Time frame: At the time of embryo transfer and the impact of pregnancy test result 12 days after the mebryo transfer
Embryo retained in the catheter
Embryo retained in the catheter
Time frame: Number of patients who underwent embryo transfer and the embryo was retained in the catheter at the time of embryo transfer and the impact of pregnancy test result 12 days after the mebryo transfer