Staphylococcus lugdunensis is a coagulase-negative staphylococcus belonging to the human commensal cutaneous flora, and has been little studied in the field of prosthetic joint infections. However, it shares many virulence traits with Staphylococcus aureus, including many adhesins and its ability to form biofilm, and the few series of cases reports a significant failure rate.
Study Type
OBSERVATIONAL
Enrollment
84
description of prosthetic joint infection with Staphylococcus lugdunensis
Hospices Civils de Lyon
Lyon, France
Rate of PJI infection with Staphylococcus lugdunensis
proportion of patients having PJI infection with Staphylococcus lugdunensis, alone or with other bacteria
Time frame: between 2010 and 2020
Description of PJI infection with Staphylococcus lugdunensis : type
type of PJI : knee or hip prosthesis
Time frame: Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption
Description of PJI infection with Staphylococcus lugdunensis : evolution
evolution of PJI :evolution between prosthesis placement and the onset of symptoms, gateway to infection
Time frame: Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption
Description of patients with PJI infection due to Staphylococcus lugdunensis
type of patients: age, CMI
Time frame: Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption
Description of patients with PJI infection due to Staphylococcus lugdunensis : follow up
duration of the follow up of patients
Time frame: Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption
Description of patients with PJI infection due to Staphylococcus lugdunensis : medical treatment
description and duration of antibiotics
Time frame: Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption
Description of patients with PJI infection due to Staphylococcus lugdunensis : surgical treatment
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description of surgery performed : DAIR, one-step exchange, two-step exchange
Time frame: Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption
rate of treatment failure
Treatment failure is defined by local clinical and/or microbiological relapse; and/or need for additional surgery; death of septic origin
Time frame: Outcome is measured at the end of follow-up (usually between 12 and 24 months after antibiotic therapy disruption