This study is performed to investigate the effect of opioid-free general anesthesia on the recovery quality after gynecological laparoscopy.
The quality of recovery after the surgery is assessed using the QoR 40. In addition, the various kinds of cytokine are assessed for the ancillary study.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
TRIPLE
Enrollment
78
dexmedetomidine iv bolus followed by the infusion of 0.1-1 ug/kg/hr during general anesthesia
lidocaine iv bolus followed by the infusion of 1.5 mg/kg/hr during general anesthesia
remifentanil iv infusion of 0.5-5 ng/ml (effect site concentration using TCI) during general anesthesia
Seoul St.Mary's Hospital
Seoul, Seocho-gu, South Korea
Seoul St.Mary's Hospital
Seoul, Seocho-gu, South Korea
the quality of recovery
The quality of recovery is assessed using questionnaire. This questionnaire includes 40 items. The score range is from 40 to 200. The higher score means the better quality of recovery after surgery.
Time frame: at 24 hour after the completion of surgery
cytokine
as ancillary study, to assess the various kinds of cytokines such as epinephrine, norepinephrine, interleukin-10, tumor necrosis factor-alpha.
Time frame: during surgery
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