Critically ill covid-19 patients may require respiratory support including mechanical ventilation. After an initial period with an endotracheal tube, a tracheotomy is performed in order to reduce potential airway complications, reduce the need of sedation and facilitate the monitoring and recovery. The optimal timing of this surgical procedure is, however, still unknown. The aim of this randomized, controlled trial is to compare the outcome of early (within 7 days after intubation) vs late (at least 10 days after intubation) tracheotomy in covid-19 patients. The need for mechanical ventilation, sedation, additional oxygen support, frequency of complications, duration at the ICU and mortality through the ICU stay will be evaluated and compared.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
150
Surgical procedure to secure airway
Sahlgrenska University Hospital
Gothenburg, Sweden
Mechanical ventilation
Number of days with mechanical ventilation
Time frame: Through the individual ICU stay assessed up to 60 days
ICU stay
Number of days at ICU
Time frame: Through the individual ICU stay assessed up to 60 days
Oxygen support
Number of days with need of additional oxygen support
Time frame: Through the individual ICU stay assessed up to 60 days
Sedation
Number of days with the need of sedation
Time frame: Through the individual ICU stay assessed up to 60 days
Adverse events
Various adverse events associated with the tracheotomy/tracheostomy
Time frame: Through the individual ICU stay assessed up to 60 days
Mortality
Mortality
Time frame: Through the individual ICU stay assessed up to 90 days
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