Supplementation After Bariatric Surgery

Region Östergötland260 enrolled

Overview

The aim of this study is to assess medication adherence to vitamin and mineral supplements after bariatric surgery and identify factors that may influence adherence. All study participants are prescribed life-long treatment with daily oral vitamin B12 and Calcium/Vitamin-D. Menstruating women are also prescribed daily oral iron supplementation. Post-operative adherence rate is retrieved from Pharmacy refill data, collected from the Swedish Prescribed Drug Register, the five first years after bariatric surgery.

The aim of this study is to assess medication adherence to vitamin- and mineral supplementation after bariatric surgery, identify factors that may influence adherence, as well as study the development of micronutrient deficinencies detectable by blood sampling. All study participants are prescribed life-long treatment with daily oral vitamin B12 and Calcium/Vitamin-D. Menstruating women are also prescribed daily oral iron supplementation. Post-operative adherence rate is retrieved from pharmacy refill data, collected from The Swedish Prescribed Drug Register, at one, two and five years after bariatric surgery.

Study Type

OBSERVATIONAL

Enrollment

260

Conditions

Bariatric Surgery Micronutrient Deficiencies Obesity

Interventions

Gastric Bypass, Sleeve GastrectomyPROCEDURE

Lifelong vitamin and Mineral supplementation

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Informed consent * Patients subjected to bariatric surgery at Vrinnevi Hospital, Norrköping, Sweden Exclusion Criteria: * Unable to read and understand Swedish

Locations (1)

Department of Surgery, Vrinnevi Hospital

Norrköping, Sweden

Outcomes

Primary Outcomes

Adherence to vitamin and mineral supplementation

Implementation (Continuous multiple-interval measures of medication availability/gaps, CMA),

Time frame: 5 years

Time to initiation

Initiation (time to initiation)

Time frame: 1 year

Time to discontinuation

Discontinuation (Time to discontinuation)

Time frame: 5 years

Secondary Outcomes

Self reported Adherence to vitamin-and mineral supplementation

Medication Adherence Report Scale (MARS-5) score 1-25, higher scores mean a better outcome

Time frame: 5 years

Hemoglobin (Hb)

g/L

Time frame: 5 years

Iron status

µmol/L

Time frame: 5 years

s-folate

nmol/L

Time frame: 5 years

p-calcium

mmol/L

Time frame: 5 years

s-albumin

g/L

Time frame: 5 years

s-cobolamin

pmol/L

Data from ClinicalTrials.gov

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