Comparisons of the Impact of Duloxetine Versus Imipramine on Therapeutic Efficacy, Psychological Distress, Sexual Function, Urethral and Bladder Wall Structure and Blood Flow in Women With Stress Urinary Incontinence: a Randomized Controlled Study

Far Eastern Memorial Hospital

Overview

To assess the impact of Duloxetine and Imipramine on therapeutic efficacy, psychological distress, sexual function, bladder wall structure and blood flow in women

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Conditions

Stress Urinary Incontinence

Interventions

DuloxetineDRUG

Duloxetine 30 mg qd

ImipramineDRUG

Imipramine 25mg qd

Eligibility

Sex: FEMALEMin age: 25 Years

Medical Language ↔ Plain English

Inclusion Criteria: \- Stress urinary incontinence Exclusion Criteria: 1. Take monoamine oxidase 2. Myocardial infarction critical,cardiovascular insufficiency (such as room blocking, arrhythmia, blood-soaked heart failure, myocardial infarction, stroke and excessive heartbeat). 3. Allergy to duloxetine or imipramine 4. Uncontrolled angular glaucoma patients 5. Pregnant women

Locations (1)

Department of Obstetrics and Gynecology, Far-Eastern Memorial Hospital

Banqiao District, New Taipei, Taiwan

Outcomes

Primary Outcomes

the score of International Consultation on Incontinence Questionnaire-Urinary Incontinence

Between-group difference in the score of International Consultation on Incontinence Questionnaire-Urinary Incontinence

Time frame: 8 weeks

Secondary Outcomes

the score of Urgency Severity Scale

Between-group difference in the score of Urgency Severity Scale

Time frame: 8 weeks

Data from ClinicalTrials.gov

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