the Effect of Different Mechanical Ventilation Modes on Optic Nerve Diameter and Conscious Functions

Bursa Yuksek Ihtisas Training and Research Hospital60 enrolled

Overview

During surgery, researchers use different methods in respiratory equipment. In the study researchers examine the effects of these methods on intraocular pressure changes by looking at the intraocular nerve diameter. Then look at the effects of these effects on patients conscious functions by asking some questions.

According to the mechanical ventilator application to be applied to the patients; Group P (n: 30) pressure controlled ventilation (PCV), Group V (n: 30) volume controlled ventilation (VCV) are randomly assigned to two groups. General anesthesia will be applied to all patients. Mechanical ventilation settings will be able to 8ml / kg TV (tidal volume). Demographic data (age, gender, weight, height) of patients, duration of surgery and peroperative complications will be recorded choosen time intervals.T0: awake, T1: 5th min after induction, T2: Gas insufflation start in supine position, T3: Maximum gas pressure is reached in reverse trendelenburg position, T4:Before extubation. SAB, DAB, OAB, KAH, SpO2, Ppeek, PEEP, EtCO2, optic nerve diameter will be recorded at same times. Cognitive function test will be performed at postoperative 24th hour for comparing the first awaken routin MMDT (Mini Mental Status Detection) scale. The same test will be repeated for patients who are called for routine general surgery outpatient control 3 months after surgery.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

Conditions

Mechanical Ventilation

Interventions

The Effect of Different Mechanical Ventilator Modes on Optic Nerve Diameter and Cognitive Functions in Laporoscopic Cholecystectomy OperationsPROCEDURE

The Effect of Different Mechanical Ventilator Modes on Optic Nerve Diameter and Cognitive Functions in Laporoscopic Cholecystectomy Operations

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * ASA I-II * 18-65 years old Exclusion Criteria: * Unable to cooperate * Presence of eye disease (detachment, retinapathy, glaucoma) * Presence of a previous eye operation * Those with symptoms of KIBAS (intracranial pressure increase syndrome) (Intracranial lesion, previous cerebrovascular diseases) * BMI (body mass index\> 40 kg / m2 * Obstructive and restrictive lung disease * Pulmonary Hypertension * Congestive Heart Failure

Locations (1)

University of Health Sciences Bursa Yüksek İhtisas Training and Research Hospital

Bursa, Turkey (Türkiye)

Outcomes

Primary Outcomes

Optic nerve sheath diameter (milimeter)

Optic nerve sheath diameter; It was measured from the optic nerve sheath 3 mm behind the optic disc from the closed upper eyelid. T0: Awake, T1: 5th minute after induction, T2: Gas insufflation start in supine position, T3: Maximum gas pressure is reached in reverse trendelenburg position, T4: Before extubation in supine position. A typical optic nerve sheath is generally less than 5 mm in diameter and diameters greater than 5.5 mm predict an ICP of \>20 cmH2O .

Time frame: 2 hours operation time

Cognitive Function

Cognitive function test with Mini Mental Conditioning Scale was performed to the patients before the anesthesia induction and 3 months after the surgery . Mini Mental Scale points are between 0 and 30.

Time frame: 3 months after surgery

Secondary Outcomes

Peroperative Complications

Complications during the surgery (hypercapnia, hypotension,hypertension,rythm disorder) were recorded.

Time frame: 2 hours operation time

Data from ClinicalTrials.gov

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