The aim of this study will be to analyze the newly formed bone volume and density, 6 months after alveolar cleft grafting using iliac cancellous bone graft, with and without bone marrow concentrate.
Twelve patients with unilateral alveolar cleft will be enrolled in this randomized comparative study. The patients will be divided into two groups, the control (group A) who received illiac cancellous bone graft and study group who received a combination of bone marrow concentrate and illiac cancellous bone graft (group B). Cone Beam CT (CBCT) images will be done prior to surgery to asses preoperative alveolar defect volume. Six months postoperative CBCT images will be done and postoperative newly bone formed volume and density will be evaluated and bone formation ratio (BF%) will be calculated as follows: BF% = (formed volume/alveolar defect) × 100%.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
18
patients will undergo surgery to repair alveolar cleft with autogenous bone graft combined with bone marrow concentrate
patients will undergo surgery to repair alveolar cleft with autogenous bone graft
Faculty of Dentistry
Al Fayyum, Egypt
Faculty of Dentistry
Cairo, Egypt
bone volume
V= (A1xT) + ( A2 xT) + …….+ (An xT) where: V= volume A= area T= thickness of the axial C.T slice N=number of slices
Time frame: six months postoperative
bone density
the average bone density will be measured from the CBCT
Time frame: six months postoperative
bone formation ratio
BF% = (formed volume/alveolar defect) × 100%.
Time frame: six months postoperative
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