Impact of Photopheresis in the Prevention of Acute Rejection in Highly Sensitized de Novo Kidney Transplant Recipients

Inclusion Criteria: * Sensitized (cPRA ≥90%) candidates for a deceased-donor kidney transplantation * Recipients between 18 and 75 years old * Patients are able to understand and sign informed consent (Annex 1). Exclusion Criteria: * Participation in another interventional clinical trial. * Use of Rituximab or Eculizumab at the time of transplant or in the first 24 hours post-transplant. * Persons with any dependency on the researcher or employee by the responsible institution or researcher. As well as people detained by legal order.