The addition of ultrasound-induced adipose tissue cavitation (UATC) at the level of the abdominal subcutaneous adipose tissue may seem relevant as an additive treatment option to exercise intervention in individuals with obesity. However, whether individuals with obesity who participate in an exercise intervention and additionally undergo UATC, are more likely to develop a metabolically healthy phenotype, as opposed to subjects with obesity undergoing exercise training or UATC only, remains to be studied. Therefore, the first aim of this study is to examine the impact of combined UATC during exercise intervention on abdominal subcutaneous and whole-body adipose tissue mass, quality of life and cardiometabolic risk in individuals with abdominal obesity.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Enrollment
28
Exercise training intervention with ultrasound induced adipose tissue cavitation
Exercise training intervention with ultrasound induced adipose tissue cavitation
Hasselt University
Diepenbeek, Belgium
DEXA scan
Body composition (fat mass, fat free mass, android and gynoid fat mass), clinical measures (waist circumference, hip circumference, weight, height)
Time frame: baseline
DEXA scan
Body composition (fat mass, fat free mass, android and gynoid fat mass), clinical measures (waist circumference, hip circumference, weight, height)
Time frame: week 12
Fasting blood sample
(glycated haemoglobin)
Time frame: Baseline
Fasting blood sample
(glycated haemoglobin)
Time frame: week 12
lipid profile
total LDL, HDL, triglycerides
Time frame: Baseline
lipid profile
total LDL, HDL, triglycerides
Time frame: week 12
kidney function
urea, creatinine
Time frame: Baseline
kidney function
urea, creatinine
Time frame: week 12
inflammation
CRP
Time frame: Baseline
inflammation
CRP
Time frame: week 12
Bloodpressure
systolic and diastolic blood pressure
Time frame: Baseline
Bloodpressure
systolic and diastolic blood pressure
Time frame: Week 12
oral glucose tolerance test
glucose and insulin levels at 0, 15, 30, 45, 60, 90 and 120 min post glucose load
Time frame: Baseline
oral glucose tolerance test
glucose and insulin levels at 0, 15, 30, 45, 60, 90 and 120 min post glucose load
Time frame: week 12
Overall physical fitness
Maximal oxygen uptake (during cardiopulmonary exercise testing)
Time frame: Baseline
Overall physical fitness
Maximal oxygen uptake (during cardiopulmonary exercise testing)
Time frame: week 12
Overall physical fitness
Maximal resistance (during cardiopulmonary exercise testing)
Time frame: Baseline
Overall physical fitness
Maximal resistance (during cardiopulmonary exercise testing)
Time frame: week 12
Overall physical fitness
Maximal heart rate (measured by electrocardiogram)
Time frame: Baseline
Overall physical fitness
Maximal heart rate (measured by electrocardiogram)
Time frame: week 12
SF-36 questionaire
Quality of Life questionaire, a 36-item, patient-reported survey of patient health. The SF-36 is a measure of health status
Time frame: Baseline
SF-36 questionaire
Quality of Life questionaire, a 36-item, patient-reported survey of patient health. The SF-36 is a measure of health status
Time frame: week 12
Food intake
3-day food diary
Time frame: Baseline
Food intake
3-day food diary
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Time frame: week 12