Evolution of Cochleovestibular Schwannomas

University Hospital, Strasbourg, France140 enrolled

Overview

Investigators want to know the natural history of the vestibular schwannomas: increasing, decreasing or stability, by monitoring more than 3 MRIs during a span of more than 2 years. They will obtain 3 groups: the volume increasing schwannomas which will be the most important group, the schwannomas that will be stable and a small group where the schwannomas will decrease. The secondary purpose is that the investigators want to know the threshold values: a minimum volume under which we are sure that the schwannoma will not increase, a maximum value where it will increase and if its evolution can be correlated to clinical or radiological criteria.

Study Type

OBSERVATIONAL

Enrollment

140

Conditions

Schwannoma

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age over 18 years * having a typical vestibular schwannoma diagnosis during the first MRI, having a minimum of 3 internal auditory canal MRIs on the same machine (Signa HDxt, General Electric, Strasbourg, France) ) at the Hôpitaux Universitaires de Strasbourg * patients consenting to participate Exclusion Criteria: * intra-labyrinthical extension * treatment before the 3 MRIs * no injection of gadolinium * atypical diagnosis

Locations (1)

Service Imagerie 1

Srtrasbourg, Strasbourg, France

RECRUITING

Outcomes

Primary Outcomes

Presence or absence of intra labyrinthine vestibular nerve tumor using T2 FIESTA

Time frame: 1 hour after the realization of the MRI

Central Contacts

Aïna VENKATASAMY, MD

CONTACT

33 3 88 12 78 65 aina.venkatasamy@chru-strasbourg.fr

Saïd CHAYER, PhD, HDR

CONTACT

33 3 88 11 66 90 said.chayer@chru-strasbourg.fr

Data from ClinicalTrials.gov

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