NLR has previously been observed to correlate with complications in upper GI (1) and colorectal (2) surgery. The investigators sought to assess if a similar correlation can be identified in emergency general surgical patients and if the presence of suspected or confirmed COVID-19 may impact on this. Given the heterogeneity of emergency general surgery the investigators therefore plan to perform a retrospective review of patients having emergency laparotomies only at a single NHS site during COVID-19 pandemic. Assessment of outcomes and Neutrophil:lymphocyte ratio as a predictor of outcomes will be completed. Outcomes will be completed in line with the recent COVIDSurg study criteria (3). The primary outcome is 30-day mortality. Secondary outcomes are 7-day mortality, re-operation, length of stay, post-operative respiratory failure, post-operative ARDS (Acute Respiratory Distress Syndrome), post-operative sepsis and ITU (Intensive Therapy Unit)/HDU (High Dependency Unit) admission.
Study Type
OBSERVATIONAL
Enrollment
94
All adult patients undergoing emergency laparotomy
Queen's Hospital
Romford, United Kingdom
30-day mortality
Mortality
Time frame: 30 days
7-day mortality
Mortality
Time frame: 7 days
Number of participants returning to theatre
Re-operation
Time frame: 30 days
Length of stay
Inpatient stay during index admission
Time frame: 30 days
Post-operative respiratory failure
Presence of respiratory failure in the post-operative period as defined in the clinical notes or discharge summaries
Time frame: 30 days
Post-operative ARDS
ARDS diagnosed radiologically
Time frame: 30 days
Post-operative sepsis
Presence of sepsis in the post-operative period as defined in the clinical notes or discharge summaries
Time frame: 30 days
ITU/HDU admission
ITU/HDU admission post-operatively
Time frame: 30 days
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