The Effect Of Preoperative Parameters On Success After DMEK Surgery

N/ACompletedNCT04420429

Beyoglu Eye Research and Education Hospital43 enrolled

Overview

The aim of this study is to evaluate the effect of preoperative parameters on surgical results in Descemet Membrane Endothelial Keratoplasty (DMEK) surgery.

In patients undergoing Descemet Membrane Endothelial Keratoplasty (DMEK) surgery; preoperative anterior chamber depth, angle parameters, axial length and corneal parameters will be evaluated. The effects of these parameters on surgical results will be examined.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Fuchs' Endothelial Dystrophy Pseudophakic Bullous Keratopathy Descemet's Membrane; Defect Herpetic Keratitis Angle's Classification Endothelial Dysfunction

Interventions

Descemet membrane endothelial keratoplasty (DMEK)PROCEDURE

All participants underwent DMEK surgery

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Scheduled to undergo Descemet membrane endothelial keratoplasty(DMEK) * aged 18 old older Exclusion Criteria: * Patients with corneal pathology other than endothelial insufficiency * Glaucoma patients, * Patients who have previously had any keratoplasty procedure

Locations (1)

Beyoğlu Eye Training and Research Hospital

Istanbul, Turkey (Türkiye)

Outcomes

Primary Outcomes

Change in visual acuity

Change from baseline

Time frame: Baseline and after surgery 1, 3, 6, and 12 months

Change in endothelial cell density

Change from baseline

Time frame: after surgery 1, 3, 6, and 12 months

Secondary Outcomes

Change in maximum (steepest) and minimum (flattest) keratometry values in the central corneal zone

Change from baseline

Time frame: Baseline and after surgery 1, 3, 6, and 12 months

Change in anterior chamber depth

Change from baseline

Time frame: Baseline and after surgery 1, 3, 6, and 12 months

Change in axial length

Change from baseline

Time frame: Baseline and after surgery 1, 3, 6, and 12 months

Change in central pachymetry

Change from baseline

Time frame: Baseline and after surgery 1, 3, 6, and 12 months

Change in intraocular pressure

Change from baseline

Time frame: Baseline and after surgery 1, 3, 6, and 12 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.