The study objectives are to descript clinical, biological and echocardiographic features of an acute myocarditis in children in the context of COVID-19 and to identify the underlying mechanism : direct viral damage and/or inadequate host response risk.
An unexpected increase of shock with fever in children suspected to be infect by the COVID-19 is observed. These children present with similar symptoms and seem to have similar clinical time course. This unexpected phenomenon needs to be extensively described in order to further the knowledge of unusual COVID-19 presentation in children. The study consists an extensive retrospective data collection from April 2020 till the end of the main SARS-Cov-2 outbreak, from medical file of children have exhibited acute myocarditis and cared in 4 pediatric intensive care units of Assistance Publique-Hôpitaux de Paris of Ile-de-France region. The study objectives are to descript clinical, biological and echocardiographic features of an acute myocarditis in children in the context of COVID-19 and to identify the underlying mechanism : direct viral damage and/or inadequate host response risk.
Study Type
OBSERVATIONAL
Enrollment
20
Hôpital Bicêtre
Le Kremlin-Bicêtre, France
Hôpital Armand Trousseau
Paris, France
Hôpital Necker-Enfants Malades
Paris, France
Hôpital Robert Debré
Paris, France
Acute myocarditis
Occurrence, description and time course of acute myocarditis
Time frame: 7 days
Multi-systemic inflammatory syndrome
Occurrence, description and time course of multi-systemic inflammatory syndrome, features of Kawasaki disease
Time frame: 7 days
Kawasaki disease
Occurrence, description and time course of features of Kawasaki disease
Time frame: 7 days
Results of SARS-CoV-2
Results of SARS-CoV-2 screening either by PCR or antibodies serological assay
Time frame: 7 days
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