A randomized, double-blind, placebo trial was adopted, and cardiopulmonary exercise load test (CPET) was used to detect peak oxygen uptake (PeakVO2) and exercise metabolic equivalent (METs) to confirm the clinical effect of Zhenyuan capsule on improving cardiopulmonary endurance in patients with coronary heart disease of qi deficiency and blood stasis.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
100
0.25g/ tablets, 2 tablets / TID, for 12 weeks
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Beijing, China
Cardiopulmonary function index change
Peak Oxygen Uptake(Peak VO2);Heart rate、Stroke volume and arteriovenous oxygen difference will be combined to report VO2 peak in mL/kg/min(milliliters of oxygen per kilogram of body weight per minute );
Time frame: Change from Baseline VO2 peak at 12 weeks / 16 weeks after drug treatment;
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