The study will investigate the effect of a mix of fibers and probiotics on faecal microbiota challenged by an environmental stress
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
20
A blend of fibers and seven probiotics
Société des produits Nestlé/Metabolic Unit
Lausanne, Switzerland
Minimizing microbiota composition change
Shotgum metagenomics
Time frame: Daily from Day -4 to day + 7 (Day 0 is the start of the challenge)
Increased intestinal microbiota diversity
Measured by the Shannon diversity index
Time frame: Daily from Day -4 to day + 7 (Day 0 is the start of the dietary challenge)
Increased microbiota gene richness
Measured by gene counts from metagenome sequencing of the fecal microbiota
Time frame: Daily from Day -4 to day + 7 (Day 0 is the start of the dietary challenge)
Gut comfort
Assessed each Gastrointestinal Symptoms (VOMITING, NAUSEA, AUDIBLE BOWEL SOUNDS, FLATULENCE, ABDOMINAL CRAMPS, BLOATING ) with a scale (from 0 to 10, 10 being the worst outcome)
Time frame: Daily from Day -10 to day + 7 (Day 0 is the start of the dietary challenge)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.