The study aims to identify environmental factors and genetic (gene mutation and gene expression) changes, which influencing the course of the disease the new type of coronavirus infection COVID-19 in patients nationwide in a multicenter study. At first in the study will be performed 200 patients, selected for a homogeneous groups on the basis of the patient's anamnestic data, genetic testing. Following the interim analysis, based on the results, another 800 people are planned to involve.
Study Type
OBSERVATIONAL
Enrollment
1,000
University of Pécs 1st Department of Internal Medicine Intensive Care Unit
Pécs, Hungary
University of Pécs First Department of Internal Medicine
Pécs, Hungary
Identification of genetic factors determining the course of the disease in case of COVID-19
Exploring genotype-phenotype connections based on anamnestic data of patients and joint bioinformatics analysis of its genetic variants
Time frame: 2020. December
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University of Pécs Infection Department of the Coronavirus Center
Pécs, Hungary
University of Pécs Institute of Laboratory Medicine
Pécs, Hungary
University of Pécs Szentágotahi Research Centre
Pécs, Hungary
University of Pécs Szentágothai Research Centre Genomics and Bioinformatics Core Facility
Pécs, Hungary
University of Szeged Szentágothai Research Centre Virology Research Group
Pécs, Hungary
University of Szeged Department of Anaesthesiology And Inthensive Therapy
Szeged, Hungary
University of Szeged Department of Dermatology and Allergology
Szeged, Hungary
University of Szeged Department of Medical Biology
Szeged, Hungary
...and 4 more locations