Portal Vein Pulsatility Flow in Pregnancy

University Hospital, Basel, Switzerland80 enrolled

Overview

This study is to investigate if portal vein pulsatility fraction can be measured in pregnancy and if it increases during the course of pregnancy as would be expected by the physiologic increase in blood volume that happens during pregnancy. Portal vein pulsatility fraction is measured in non-pregnant controls and in women in the 1st, 2nd and 3rd trimester of pregnancy.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Pregnancy

Interventions

ultrasoundOTHER

portal vein pulsatility fraction (percent) measured with ultrasound

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Ability to give informed consent * American Society of Anesthesiologists (ASA) Class I and II * Singleton pregnancy during 1st, 2nd or 3rd trimester or healthy non-pregnant females of childbearing age as controls Exclusion Criteria: * Inability to give informed consent * Multiple gestation * Significant co-morbidities (e.g. cardiac abnormalities, cardiac dysfunction, arrhythmias, severe asthma, renal insufficiency) * High risk pregnancies (e.g. pre-eclampsia, gestational hypertension, HELLP, gestational diabetes) * Body-Mass-Index (BMI) \< 18kg/m2 or \>40kg/m2

Locations (1)

Department of Anesthesiology, University Hospital Basel

Basel, Switzerland