Adenoid Hypertrophy, Respiratory Complications and Correlation With Infant Feeding Position

Hadassah Medical Organization500 enrolled

Overview

500 children aged 0-5 years followed since birth by Principal Investigator (PI)since January1, 2003 till December 31, 2018 and diagnosed with adenoid hypertrophy (AH) (study group) and 500 children aged 0-5 years followed by principal investigator during the same years and diagnosed as urinary tract infection (UTI), gastroenteritis (GE), diarrhea, vomiting but without AH (control group) were compared. Morbidity and treatment will be compared and correlated with gastro-esophageal reflux (GER), allergy and infant feeding position during the first few years of life in the two groups.

The 2 groups are children aged 0-5 years and treated by PI and followed since birth during years 2003-2018. Study group consists of children diagnosed at least 2 times as AH and control group as similar children with UTI, GE, vomiting or diarrhea. Respiratory problems (pneumonia, bronchopneumonia, bronchitis), ear problems (otitis media OM, serous OM), antibiotic treatment, use of bronchodilators, inhaled corticosteroid (ICS), chest X-rays, anomalous laboratory results, emergency room visits and hospitalization rates will be compared in the two groups, together with details concerning feeding position during the first years of life. Correlation between morbidity, degree of nasopharyngeal obstruction, allergy, GER and supine feeding position, will be evaluated.

Study Type

OBSERVATIONAL

Enrollment

500

Conditions

Adenoid Hypertrophy

Interventions

Eligibility

Sex: ALLMin age: 1 MonthMax age: 5 Years

Medical Language ↔ Plain English

Inclusion Criteria: Study group: Young children with diagnosis of adenoid hypertrophy followed by PI Control group: young children with diagnosis of UTI, GE, vomiting or diarrhea followed by PI Exclusion Criteria: Children with cystic fibrosis, primary dyskinesia, immune deficiency, congenital anatomical malformations of nasal or airway passages. Children older than 6 months of age when starting to be followed by PI.

Outcomes

Primary Outcomes

Respiratory complications

Number of participants with Pneumonia, bronchitis

Time frame: 3 years

Ear complications

Number of participants with otitis media, serous otitis media

Time frame: 3 years

Secondary Outcomes

Correlations between morbidity, degree of adenoid hypertrophy and feeding position

Correlation between respiratory morbidity, ear morbidity, laboratory and chest \& nasopharynx X-rays with feeding position in first year of life Correlation between respiratory and ENT morbidity with degree of adenoid obstruction, allergy, GER and infant feeding position during the first 2 years of life.

Time frame: 5 years