Assessment of Functional Capacity, Pain, Cognitive and Respiratory Functions in Lung Cancer Survivors

N/ACompletedNCT04431921

Hacettepe University60 enrolled

Overview

Serious side effects occurs with disease and treatments in survival after lung cancer. For this reason, functional capacity, cognitive status, pain perception and respiratory functions may be affected in lung cancer. The purpose of this study was to evaluate respiratory function, respiratory muscle strength and endurance, functional capacity, pain, cognitive status level, and physical activity in lung cancer patients and compare with the findings of healthy subjects

This study was participated lung cancer patients survivors. Patients' pulmonary function test, functional capacity, respiratory muscle strength and endurance, pain and cognitive status was assessed and recorded. Pulmonary function testing (PFT), mouth pressure measurement (MIP- maximal inspiratory pressure and MEP- maximal expiratory pressure), respiratory muscle endurance test, six minute walk test (6MWT) and pain threshold and tolerance test were used. In addition to physiological measurements, the Montreal Cognitive Assessment (MoCA) scale was used to evaluate cognitive status, the International Physical Activity Questionnaire (IPAQ) was used to determine the level of physical activity.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Lung Neoplasm Survivorship

Interventions

Functional capacityDIAGNOSTIC_TEST

Six minute walk test used assessment of functional capacity. For respiratory function mouth pressures, for cognitive functions MoCA scale and for pain assessment pain threshold and tolerance test assessed.

Eligibility

Sex: ALLMin age: 45 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Cooperation * lung cancer patients who had a stable condition Exclusion Criteria: * Active cancer treatments * Brain metastasis story * Any orthopedic disease impairs walking, balance

Locations (1)

Hacettepe University

Ankara, Turkey (Türkiye)

Outcomes

Primary Outcomes

Functional capacity

Six minute walk test: Distance walked in six minute was recorded

Time frame: 15 minutes

Secondary Outcomes

Respiratory muscle strength assessment

Respiratory muscle strength was evaluated by measuring maximal inspiratory pressure (MIP) and maximal expiratory pressure (MEP).

Time frame: 10 minutes

Respiratory muscle endurance

Pressure time unit: A constant load test was used to evaluate respiratory muscle endurance. Using a PowerBreathe device (HaB International Ltd., Southam, UK), the participants were asked to breathe maintaining a constant threshold (60% of MIP) until task failure, and the test duration was recorded. Results were obtained by multiplying the set pressure by the test duration

Time frame: 10 minutes

Pulmonary functions test

pulmonary functions assessment via spirometry

Time frame: 15 minutes

Cognition using MoCA-Test

Cognitive function was evaluated with the secreening tool the Montreal Cognitive Assessment (MoCA). The MoCA is a 30-point screening tool. Higher scores mean a better outcome.

Time frame: 10 minutes

Pressure pain threshold assessment

Pressure pain threshold was evaluated via algometer. The pressure at which the individual first reported pain was recorded.

Time frame: 15 minute

Pressure pain tolerance assessment

Pressure pain tolerance test was evaluated via algometer.The pressure at which the individual last pressure point at which they could endure the pain was recorded.

Data from ClinicalTrials.gov

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