Effects of tDCS in M1 and DLPFC on Pain Processing in Healthy Volunteers

Universidad Rey Juan Carlos30 enrolled

Overview

The purpose of this study is to evaluate the effects of a direct current applied transcranial over two cortical areas on healthy volunteers' pain processing.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

QUADRUPLE

Enrollment

Conditions

Pain Processing in Healthy Volunteers

Interventions

Transcranial direct current stimulationDEVICE

Direct current application over the scalp to stimulate and change the excitability of the cortical areas underneath the electrodes (in this case left primary motor cortex and left dorsolateral prefrontal cortex).

Eligibility

Sex: ALLMin age: 18 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Age between 18 and 40 years * Comprehension of the study tasks Exclusion Criteria: * Presence of pain in the previous 6 months * Altered sensitivity in the tested regions * Intolerance to electrotherapy * Presence of pacemakers or any other implanted device * Ulcers or scars in the skin at the location of the electrodes * Treatment with direct current stimulation within one week * Pregnancy * Frequent headaches * Epilepsy * History of neuromuscular disease * Previous clinical history of cervical surgery * Injuries or surgery affecting the upper limb * diabetes mellitus * Cardiovascular diseases * Oncological diseases * Consumption of analgesic drugs 7 days before the study

Locations (1)

Universidad Rey Juan Carlos

Alcorcón, Madrid, Spain