Hypertension and Controlled Hypotension in the Elderly

Zhang Lei98 enrolled

Overview

Comparision of Exposed Factors of Preoperative Hypertension and Intraoperative Controlled Hypotension on Postoperative Delirium in the Elderly under Radical Resection of Head, Neck and Maxillofacial Tumor

Postoperative delirium has a higher incidence in elderly patients after general anesthesia，and It is closely related to the type of surgery, the length of surgery, and the patient's physique.Because head and neck maxillofacial radical surgery requires free flap transplantation and longer duration,and hemorrhage is more when the primary focus is removed，Intraoperative blood pressure reduction is needed to reduce bleeding，therefore, hypoperfusion of craniocerebral blood flow will occur.Low cerebral perfusion is closely related to the occurrence of postoperative delirium.Patients undergoing this type of surgery have more preoperative complications，hypertension is particularly common.Therefore, this study mainly studied the correlation between the preoperative blood pressure level and the controlled hypotension level in patients with radical head and neck and maxillofacial tumors and the incidence of postoperative delirium.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Delirium

Interventions

hypertensionDIAGNOSTIC_TEST

If the patient has two or more blood pressure values ≥140/90mmHg in a calm state, he is included in this group

Eligibility

Sex: ALLMin age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Patients who underwent radical anesthesia for oral and maxillofacial malignant tumors in our hospital 2. ASA grade is Ⅰ-Ⅱ 3. Patient is older than 60 years Exclusion Criteria: 1. The patient has mental and mental disorders (eg schizophrenia, Alzheimer's disease) 2. There was severe anemia before operation (Hb\<80g/L) 3. Patients had cerebral vascular complications such as cerebral infarction and lacunar infarction before operation 4. Patients who do not cooperate with this trial 5. Long-term use of sedative drugs or analgesics

Locations (1)

Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University

Shanghai, Shanghai Municipality, China

Outcomes

Primary Outcomes

Degree of delirium

From the first to the third day after surgery, the patient will be evaluated for delirium using the CAM scale.

Time frame: up to three days after surgery

Data from ClinicalTrials.gov

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