Patients will be randomly divided into 3 equal groups: Group I received ultrasound guided injection of 2 mL PRP into the affected carpal tunnel. Group II received ultrasound guided injection of 2 mL steroids (40 mg triamcinolone acetonide). Group III received ultrasound guided injection of 2 mL saline as placebo control.
Patients will be randomly divided into 3 equal groups: Group I received ultrasound guided injection of 2 mL PRP into the affected carpal tunnel. Group II received ultrasound guided injection of 2 mL steroids (40 mg triamcinolone acetonide). Group III received ultrasound guided injection of 2 mL saline as placebo control. Each group will be injected twice with 2 weeks intervals. All procedures were done after informed consent. Evaluation of the patients at baseline, 3 and 6 months after last injection was done clinically by measuring visual analogue scale (VAS), electrophysiologically (by measuring motor and sensory nerve conduction studies of median nerve using a standardized technique) and ultrasonographic study by measuring cross sectional area (CSA) of median nerve at the level of pisiform.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
90
Platelet-rich plasma (PRP) promotes angiogenesis, neurogenesis, and nerve regeneration, also it could reduce swelling and inflammation of the flexor tenosynovitis.
40 mg triamcinolone acetonide
Saline
Tanta University Hospital
Tanta, Egypt
visual analogue scale
Scale for assessement the degree of pain along 0-10 scale
Time frame: Change from 3 months after last injection and 6 months after last injection
measuring motor and sensory nerve conduction studies of median nerve using a standardized technique
electrophysiologically by measuring motor and sensory nerve conduction studies of median nerve using a standardized technique
Time frame: Change from 3 months after last injection and 6 months after last injection
cross-sectional area (CSA) of the median nerve at the level of the pisiform.
ultrasonographic study by measuring cross-sectional area (CSA) of the median nerve at the level of the pisiform.
Time frame: Change from 3 months after last injection and 6 months after last injection
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