the aim of this study is clinically and radiographically evaluate the use of advance platelet rich fibrin (A-PRF) versus platelet rich fibrin (PRF) in preservation of alveolar ridge following tooth extraction
systemically healthy patients who have at least one non-restorable tooth in the upper inter-bicuspid region and are not seeking immediate or early implant treatment will be allocated in this study after performing nonsurgical periodontal therapy and preoperative periapical therapy to evaluate and improve the condition of the periodontal tissues. Anesthesia will be given then flapless atraumatic extraction using periotomes followed by forceps after luxation. For all groups, the socket will be debrided using curette then * group A, the socket will be filled with A.PRF * group B the socket will be filled with PRF. * group C no bio-additive will be added. * Criss cross horizontal mattress suture will be applied to close the extraction wound. PRF and A-PRF preparation : 10 ml of blood will be drawn from each patient by vein puncture of the antecubital vein. * Plateletr ich fibrin (PRF) is 3000 rpm and 10 minutes without addition of anticoagulant * Advanced platelet rich fibrin (A-PRF) is 1300 rpm and 8 minutes.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Enrollment
60
following atraumatic extraction of the tooth using periotomes , 10 ml of patient's blood will be drawn by vein puncture of the antecubital vein and prepared in a centrifuge at 3000 rpm for 10 minutes then criss horizontal mattress suture will be applied to close the extraction wound
following atraumatic extraction of the tooth using periotomes , 10 ml of patient's blood will be drawn by vein puncture of the antecubital vein and prepared in a centrifuge at 1300 rpm for 8 minutes then criss horizontal mattress suture will be applied to close the extraction wound
following atraumatic extraction of the tooth using periotomes, no bio-addative will be added and criss horizontal mattress suture will be applied to close the extraction wound
School of dentistry , Cairo University
Cairo, Egypt
Change in bucco-lingual dimensions
clinical measurement using bone caliper in mm numerical
Time frame: 6 months
change in alveolar bone height
radiographic measurement using CBCT in mm numerical
Time frame: 6 months
bone dentistry
radiographic measurement using CBCT
Time frame: 6 months
soft tissue healing
clinical measurement using landr et al index (healing index) in numerical
Time frame: 6 months
postoperative pain scores
clinical measurement using VAS scale in numerical where No pain (0-4 mm) - mild pain (5-44 mm) -moderate pain (45-74 mm), and severe pain (75- 100 mm).
Time frame: 2 weeks
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