Study of the Absorption, Metabolism, and Excretion Following a Single Dose of [14C]-Poziotinib in Healthy Male Subjects

Key Inclusion Criteria: * Body mass index between 18.0 and 32.0 kg/m2, inclusive * In good health at Screening and/or at Check-in * Subjects must be surgically sterile for at least 90 days, or when sexually active with female partners of childbearing and non-childbearing potential will be required to use a male condom with spermicide from CRU Check-in until 90 days after discharge. Subjects are required to refrain from donation of sperm from CRU Check-in until 90 days after discharge * Able to comprehend and willing to sign an ICF and to abide by the study restrictions * History of at least 1 bowel movement per day Key Exclusion Criteria: * Stomach or intestinal surgery or resection that would potentially alter absorption and/or excretion of orally administered drugs * Swallowing difficulties or ongoing diarrhea of any etiology * Participation in a clinical study involving an investigational drug in the past 30 days prior to dosing * Use or intend to use any medications/products known to alter drug absorption, metabolism, or elimination processes, including St. John's wort, within 30 days prior to Check-in * Use or intend to use any prescription medications/products within 14 days prior to Check-in * Use or intend to use slow-release medications/products considered to still be active within 14 days prior to Check-in * Exposure to significant diagnostic or therapeutic radiation or current employment in a job requiring radiation exposure monitoring within 12 months prior to Check-in