Given the emerging evidence on LRRK2-related biomarkers, this project will focus on identifying leucocyte and urine biomarkers that are altered by the LRRK2 G2385R variant, and investigating the effects of LRRK2 kinase inhibitor (MLi-2) on these biomarkers, using immunoblotting and mass spectrometry.
Study Type
OBSERVATIONAL
Enrollment
150
This is a non-interventional study
University of Malaya Medical Centre
Kuala Lumpur, Malaysia
RECRUITINGIdentification of monocyte-based biomarkers for LRRK2 G2385R variant
Time frame: Two years
Identification of urine-based biomarkers for LRRK2 G2385R variant
Time frame: Two years
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