This study seeks to determine how COVID-19 affects the clinical outcome of patients with chronic liver disease, and whether the clinical course of COVID-19 is influenced by underlying chronic liver disease.
Study Type
OBSERVATIONAL
Enrollment
1,025
Collected data will include demographic features, clinical characteristics, clinical outcome, medication use, COVID-19-related complications in patients with chronic liver disease.
University of Arizona,
Phoenix, Arizona, United States
All-cause mortality
Death due to any cause
Time frame: 30 days
All-cause mortality
Death due to any cause
Time frame: 1 year
Liver-related mortality
Death due to liver-related cause
Time frame: 28 days
Liver-related mortality
Death due to liver-related cause
Time frame: 1 year
Overall survival
Patients will be assessed for this outcome for up to 1 year
Time frame: Up to 1 year
Number of patients with hepatic decompensation
Onset of hepatic decompensation due to COVID-19 disease; patients will be assessed for this outcome for up to 1 year
Time frame: Up to 1 year
Number of patients requiring hospitalization
Patients will be assessed for this outcome for up to 1 year.
Time frame: Up to 1 year
Duration of hospitalization
Patients will be assessed for this outcome for up to 1 year.
Time frame: Up to 1 year
Length of intensive care unit (ICU) stay
Patients will be assessed for this outcome for up to 1 year.
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Mayo Clinic
Scottsdale, Arizona, United States
UCSF Fresno
Fresno, California, United States
University of Southern California
Los Angeles, California, United States
Stanford University
Stanford, California, United States
Georgetown University
Washington D.C., District of Columbia, United States
VA Medical Center
Washington D.C., District of Columbia, United States
University of Miami
Miami, Florida, United States
Rush University Medical Center
Chicago, Illinois, United States
The University of Kansas Medical Center
Kansas City, Kansas, United States
...and 13 more locations
Time frame: Up to 1 year
Number of participants requiring mechanical ventilation
Patients will be assessed for this outcome for up to 1 year.
Time frame: Up to 1 year