Effects of Nopal Fractions on Postprandial Glucose Regulation and Appetite Variables in Healthy Humans

Lund University24 enrolled

Overview

Postprandial effects of Nopal fractions on glucose and appetite regulation will be investigated in healthy humans, in a randomised controlled crossover trial

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

SINGLE

Enrollment

Conditions

Glucose Tolerance Appetite Sensations

Interventions

Nopal fractionsDIETARY_SUPPLEMENT

Nopal flour were divided in two fractions and mixed in two different test breads

Test product without the active componentsDIETARY_SUPPLEMENT

Test product without the active components

Eligibility

Sex: ALLMin age: 18 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Healthy * non-smokers * diet accordance with the Nordic Nutrition Recommendations * BMI: 18.5-25 kg/m2 Exclusion Criteria: * metabolic disorders * food allergies * no probiotics or other food /supplement which may interfere with the study

Locations (1)

Food Technology, engineering and Nutrition, LTH, Lund University

Lund, Sweden

Outcomes

Primary Outcomes

postprandial glucose tolerance

effects on postprandial glucose tolerance after intake of test products at breakfast. Measurements were performed at fasting (time = 0 min) and at 15, 30, 45, 60, 90, 120, 150 and 180 min.

Time frame: 0-180 min after start of the meal

postprandial insulin concentrations

effects on serum insulin concentrations after intake of test products at breakfast. Measurements were performed at fasting (time = 0 min) and at 15, 30, 45, 60, 90, 120, 150 and 180 min.

Time frame: 0-180 min

Secondary Outcomes

subjective appetite variables

Subjective appetite variables (hunger, satiety, desire to eat) after intake of test products at breakfast, using a 100 mm Visual Analogue Scale (VAS) on a white paper. Except from a center mark in the center of the scale there was no other visible marks. Measurements were performed at fasting (time = 0 min) and at 15, 30, 45, 60, 90, 120, 150 and 180 min.

Time frame: 0-180 min

Data from ClinicalTrials.gov

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