Intravenous Infusion of Lidocaine in Colonoscopy

Shandong University50 enrolled

Overview

intravenous infusion of lidocaine significantly reduce fatigue and pain and improve the patients satisfaction after sedation for colonoscopy.

This study divide patients into two groups, lidocaine group one will be given lidocaine intravenously; control group will be given saline . the difference between patients fatigue and pain will be compared. and the propofol consumption, pain after infusion of propofol, patients, endoscopists and anaesthesist satifaction, the incidence of hypotenstion, hypoxia, and bradycardia will aslo be compared between the two groups.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

TRIPLE

Enrollment

Conditions

Sedation

Interventions

placeboDRUG

the control group will be given the same volume of saline.

lidocaineDRUG

the experimental group will be given 1-1.5mg/kg lidocaine and then 2mg/kg/h

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: Inclusion Criteria: patients aged \>18 years who were scheduled for colonscopy at Qilu hospital. Exclusion Criteria:patients with ASA (American Society of Anesthesiologists) Class 4 or 5, pre-existing hypoxemia (SpO2 \<90%), hypotension (systolic blood pressure \<90 mm Hg), bradycardia (HR\<50 beats/min), uncontrolled hypertension (SBP \>170 mm Hg, diastolic blood pressure\>100 mm Hg), severe renal or liver failure, pregnancy or lactation, allergy to lidocaine, atrioventricular block, epilepsy, and inability to give informed consen \-

Locations (1)

Department of Gastroenterology, Qilu Hospital, Shandong University

Jinan, Shandong, China

RECRUITING

Outcomes

Primary Outcomes

fatigue score after colonoscopy

fatigue were measured on a 0-10VAS at arrival in the recovery room ,30min later

Time frame: half a year

Secondary Outcomes

pain socre after colonoscopy

pain were measured on a 0-10VAS at arrival in the recovery room ,30min later

Time frame: half a year

Central Contacts

Jing Liu, MD

CONTACT

+86-18560083755 liujingqilu@126.com

yanqing li, phD

CONTACT

86-531-82169236 liyanqing@sdu.edu.cn

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.