Activation of miRNA and Proteins After Acute Experimental Pain. (miRNA: Micro RNA)

Inclusion Criteria: * Healthy men and women in the age 18-80 years * Speak and understand English Exclusion Criteria: * Acute and chronic pain * Pregnancy or breastfeeding * Drug addiction defined as the use of cannabis, opioids or other drugs * Present or previous history of neurological, dermatological, immunological, musculoskeletal, cardiac disorder or mental illnesses that may affect the results (e.g. Neuropathy, muscular pain in the upper extremities, etc.) * Lack of ability to cooperate * Current use of medications that may affect the trial, such as antipsychotics and pain killers as well as systemic or topical steroids and anti-inflammatory drugs. * Skin diseases * Consumption of alcohol or painkillers 24 hours before the study days and between these * Participation in other trials within 1 week of study entry (4 weeks in the case of pharmaceutical trials)