Study of Seroprevalence of Anti-SARS-CoV2 Among Children of Hospital Workers in AP-HP

N/ACompletedNCT04442087

Assistance Publique - Hôpitaux de Paris563 enrolled

Overview

The purpose of this study is to define seroprevalence of anti-SARS-CoV2 among children of Hospital Workers in APHP, particularly exposed population, according to parents' SARS-CoV2 serological status.

Study Type

INTERVENTIONAL

Allocation

Purpose

BASIC_SCIENCE

Masking

NONE

Enrollment

563

Conditions

SARS-CoV2

Interventions

Serology SARS-CoV2BIOLOGICAL

Collect serum for Serology SARS-CoV2 at inclusion

Data collectionBEHAVIORAL

Collect clinical and demographic data, habitus, Lifestyle Counseling at inclusion

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: Hospital workers : 1. Individuals aged over 18, having a professional activity at the APHP (employees, interns, volunteers) 2. Affiliated to a social security regimen 3. Have at least one child under the age of 18 living in the same house. 4. have signed consent Child (ren), spouse and other member (s) residing at household: Child (ren), spouse and any other member residing in the household of a professional of the Paris Center Hospitals meeting the inclusion criteria above. Exclusion Criteria: Refuse to participate in research

Locations (1)

Centre d'investigation clinique (CIC) Necker Cochin in Necker Children's Hospital

Paris, France

Outcomes

Primary Outcomes

Seroprevalence of antibodies anti- SARS Cov2 in blood sample of children of Hospital workers

Percentage of children with seropositive in blood sample according to parents' SARS Cov2 serological status

Time frame: at inclusion

Seroprevalence of antibodies anti- SARS Cov2 in saliva sample of children of Hospital workers

Percentage of children with seropositive according in saliva sample to parents' SARS Cov2 serological status

Time frame: at inclusion

Secondary Outcomes

Number of Asymptomatic Children with a positive seroloy

Time frame: At inclusion

Number of severely symptomatic Children with a positive serology

Time frame: At inclusion

Prevalence of different clinical symptoms in children with a positive serology

Time frame: At inclusion

Serological result of each member of the family

Time frame: At inclusion

Number of spouses of hospital workers with a positive serology

Time frame: At inclusion

Number of Asymptomatic spouses of hospital workers with a positive serology

Time frame: At inclusion

Number of severely symptomatic spouses of hospital workers with a positive serology

Time frame: At inclusion

Comparison of Serological result obtained in blood and saliva samples

Data from ClinicalTrials.gov

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