To observe the retinal microvascular alteration during 3 months follow-up after Implantable Collamer Lens (ICL) operation in moderate and high myopia patients using quantitative optical coherence tomography angiography (OCTA) analysis.
The study object is moderate and high myopia patients, underwent ICL implantation. OCTA was used to image the superficial and deep retinal vascular plexuses before ICL implantation surgery and at 3 months follow-up. OCTA images were corrected for magnification, skeletonized, separated the large vessels and partitioned. Retinal microvascular density was measured by using fractal dimension analysis. The aim of this study was to uncover potential retinal vascular network alterations induced by ICL implantation surgery.
Study Type
OBSERVATIONAL
Enrollment
25
AngioVue (Optovue, Fremont, CA, USA) was used to capture the OCTA images before ICL surgery and at 3 months follow-up.
Peking University Third Hospital
Beijing, Beijing Municipality, China
Retinal microvessels density
Retinal microvessels density was measured with fractal dimension analysis by using Matalb (The Mathworks, Inc., Natick, MA, USA)
Time frame: 3 months postoperatively
Best corrected visual acuity
BCVA was evaluated by decimal Snellen and converted to the logarithm of the minimum angle of resolution (logMAR) for statistical analysis.
Time frame: 3 months postoperatively
Mean refractive spherical equivalent
MRSE = Spherical power + 0.5 \* Cylindrical power
Time frame: 3 months postoperatively
Intraocular pressure
The IOP was measured using a non-contact tonometer (CT-80; Topcon, Tokyo, Japan).
Time frame: 3 months postoperatively
Vault
The central vault of the ICL (distance from posterior surface of ICL to the crystalline lens) was measured using Optical Coherence Tomography (Visante; Carl Zeiss Meditec, Jena, Germany)
Time frame: 3 months postoperatively
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.