A multicenter, retrospective clinical study was carried out in the medical records management system of 6 hospitals in Tianjin. Patients who were suffered with Coronary heart disease angina pectoris and underwent coronary angiography are collected. The investigators collect and analyze the demographics, laboratory information, clinical outcome data, and coronary angiographic data of patients. To explore the correlation between hypercholesterolemia and the degree of coronary artery stenosis of Coronary heart disease angina pectoris, and to further research the influence of hypertension on total cholesterol level and coronary artery stenosis, and provide guidance for clinical prevention and treatment.
Based on the total cholesterol level, the investigators divided patients into 3 groups: patients with TC \< 5.18 mmol/l belong to normal TC (NTC) group, 5.18 ≤ TC \< 6.19 mmol/l is borderline-high TC (BHTC) group, those with TC ≥6.19 mmol/l belong to high TC (HTC) group, and the correlation between the TC and the degree of coronary artery stenosis is evaluated. With or without hypertension will be further stratified to assess the effect of with or without hypertension on the correlation between TC levels and the degree of coronary artery stenosis. The 6 subgroups are: NTC/-HTN group, NTC/+HTN group, BHTC/-HTN group, BHTC/+HTN group, HTC/-HTN group, HTC/+HTN group. The investigators refer to the recent diagnostic guidelines for coronary heart disease angina pectoris at home and abroad. The diagnosis can be given if it meets any one or more of the following: 1. There was a clear history of old myocardial infarction. 2. Previous coronary angiography or coronary CTA examination showed that at least one major branch of coronary artery has a lumen diameter stenosis ≥50%. 3. Those with ST-segment depression or T-wave inversion on ECG after coronary revascularization. The investigators will redefined hypertension as systolic blood pressure ≥130 mmHg or diastolic blood pressure ≥80 mmHg according to the recently published 2017 ACC/AHA guidelines.
Study Type
OBSERVATIONAL
Enrollment
1,000
Tianjin University of Traditional Chinese Medicine
Tianjin, Tianjin Municipality, China
Fasting blood glucose in clinical biochemical tests.
In the hospital medical record management system, the investigators collect the fasting blood glucose data of the first day of hospitalization of the patients.
Time frame: one year
Glycated hemoglobin in clinical biochemical tests.
In the hospital medical record management system, the investigators collect the glycated hemoglobin data of the first day of hospitalization of the patients.
Time frame: one year
Total cholesterol in clinical biochemical tests.
In the hospital medical record management system, the investigators collect the total cholesterol data of the first day of hospitalization of the patients.
Time frame: one year
Triglyceride in clinical biochemical tests.
In the hospital medical record management system, the investigators collect the triglyceride data of the first day of hospitalization of the patients.
Time frame: one year
Low density lipoprotein cholesterol in clinical biochemical tests.
In the hospital medical record management system, the investigators collect the low density lipoprotein cholesterol data of the first day of hospitalization of the patients.
Time frame: one year
High density lipoprotein cholesterol in clinical biochemical tests.
In the hospital medical record management system, the investigators collect the high density lipoprotein cholesterol data of the first day of hospitalization of the patients.
Time frame: one year
C-reactive protein in clinical biochemical tests.
In the hospital medical record management system, the investigators collect the C-reactive protein data of the first day of hospitalization of the patients.
Time frame: one year
Fibrinogen in clinical biochemical tests.
In the hospital medical record management system, the investigators collect the fibrinogen data of the first day of hospitalization of the patients.
Time frame: one year
Coronary angiography data in imaging examination.
In the hospital medical record management system, the investigators collect coronary angiography data of the patient's hospitalization.
Time frame: one year
Age in demographics.
In the hospital medical record management system, the investigators collect the age data of the first day of hospitalization of the patients.
Time frame: one year
Gender in demographics.
In the hospital medical record management system, the investigators collect the gender data of the first day of hospitalization of the patients.
Time frame: one year
Ethnicity in demographics.
In the hospital medical record management system, the investigators collect the ethnicity data of the first day of hospitalization of the patients.
Time frame: one year
Weight in demographics.
In the hospital medical record management system, the investigators collect the weight data of the first day of hospitalization of the patients.
Time frame: one year
Smoking in demographics.
In the hospital medical record management system, the investigators collect the smoking data of the first day of hospitalization of the patients.
Time frame: one year
Medical history in demographics.
In the hospital medical record management system, the investigators collect the medical history data of the first day of hospitalization of the patients.
Time frame: one year
Blood pressure in demographics.
In the hospital medical record management system, the investigators collect the blood pressure data of the first day of hospitalization of the patients.
Time frame: one year
Evaluate the correlation between total cholesterol level and the degree of coronary artery stenosis
Based on the total cholesterol level, the investigators divide patients into 3 groups. According to the location and degree of the lumen stenosis, the score of the degree of each coronary artery stenosis is calculated.
Time frame: one year
Assess the effect of with or without hypertension on the correlation between total cholesterol level and the degree of coronary artery stenosis
According to with or without hypertension, the patients are further divided into 6 subgroups.
Time frame: one year
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