SRD-Part: To investigate safety, tolerability, pharmacokinetics and pharmacodynamics following single rising doses (SRD) of BI 1569912 BA/FE-Part: To investigate (a) the relative bioavailability (BA) of BI 1569912 and (b) the influence of food (FE) on the relative bioavailability of BI 1569912
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
68
BI 1569912
Placebo
Charité - Universitätsmedizin Berlin
Berlin, Germany
SRD-part: % of subjects with drug-related adverse events
Time frame: up to 14 days
BA/FE-part: AUC0-tz (area under the concentration-time curve of BI 1569912 in plasma over the time interval from 0 to the last quantifiable data point)
Time frame: up to 4 days
BA/FE-part: Cmax (maximum measured concentration of BI 1569912 in plasma)
Time frame: up to 4 days
SRD-Part: AUC0-∞ (area under the concentration-time curve of BI 1569912 in plasma over the time interval from 0 extrapolated to infinity)
Time frame: up to 4 days
SRD-Part: Cmax (maximum measured concentration of BI 1569912 in plasma)
Time frame: up to 4 days
BA/FE-Part: AUC0-∞ (area under the concentration-time curve of BI 1569912 in plasma over the time interval from 0 extrapolated to infinity)
Time frame: up to 4 days
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