The aim of this study is to compare the duration of postoperative analgesia, and any side effects of caudal dexmedetomidine versus morphine in combination with bupivacaine in pediatric patients undergoing thoracic surgeries.
The patients will be randomized in a blinded fashion to get enrolled into 2 equal groups: Group A patients (n =25) will receive caudal epidural analgesia using dexmedetomidine with bupivacaine, whereas Group B patients (n = 25) will receive caudal epidural analgesia using morphine with bupivacaine. Randomization will be achieved by using an online random number generator. Patient codes will be placed into sequentially numbered sealed opaque envelopes by a research assistant who is not involved in the study. An anesthesia resident not involved in patient management will be responsible for opening the envelope. The anesthesia resident will prepare the study drug according to the instructions contained within each envelope and give it to the anesthesiologist.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Enrollment
50
Caudal block with Dexametomedine as an adjuvant to bupivacaine.
Addition of morphine as adjuvant to bupivacaine during caudal block.
Cairo University Hospitals
Cairo, Egypt
Duration of postoperative analgesia in hours.
Duration of postoperative analgesia in hours.
Time frame: 3 months
Opioid consumption in the first 24 hours post- operative.
Opioid consumption in the first 24 hours post- operative.
Time frame: 3 months
The duration of ICU stay in days
The duration of ICU stay in days
Time frame: 3 months
Pain score FLACC from 0 to 6
Pain score FLACC from 0 to 6
Time frame: 3 months
Post operative heart rate
Postoperative heart rate in beat per minute
Time frame: 3 months
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