Liver Diseases in PLWH

First Affiliated Hospital of Zhejiang University3,000 enrolled

Overview

In Highly Active Antiretroviral Therapy era, fatty liver has become an important cause of liver function damage in people living with HIV (PLWH). There are a large number of PLWH in China who are infected with hepatitis B virus and hepatitis C virus. HIV, hepatitis B virus, hepatitis C virus, drugs, alcohol, etc. affect each other, which makes the cause, diagnosis, and treatment of liver function damage in PLWH complicated in China. The investigators plan to conduct a large-scale questionnaire survey among PLWH in Zhejiang Province to assess liver function, detect liver Injuries early, and analyze HIV, hepatitis B virus, hepatitis C virus, anti-HIV drugs, alcohol and other factors associate with liver injuries in PLWH, to provide basis for the treatment and prevention of liver disease in PLWH in eastern China.

Study Type

OBSERVATIONAL

Enrollment

3,000

Conditions

HIV/AIDS Liver Diseases

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age ≥18 years old; * Non-hospitalized patients diagnosed with HIV infection; * Sign the informed consent voluntarily. Exclusion Criteria: * Severe active infection requiring parenteral antibiotics or antifungal treatment within 30 days before the assessment; * Other major chronic diseases that may affect health-related quality of life, such as extrahepatic malignant tumors; * Psychotic patients, patients with severe cognitive or neurological deficits; * Women during pregnancy and lactation; * Those who refuse to sign informed consent.

Liver Diseases in PLWH

Overview

Conditions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Central Contacts