Results of Cold Stored Allografts in Vascular Access

Central Hospital, Nancy, France120 enrolled

Overview

Vascular access creation in patients with renal failure requiring long-term hemodialysis can be a challenge when there is no more autologous material or in case of infection, in a population undergoing long term dialysis with a longer life-expectancy. Many types of grafts have been used, with its advantages and drawbacks, such as prosthetic grafts (PTFE). Over the past decade, surgeons have used cold stored venous allografts as a biological conduit for hemodialysis, with the idea of avoiding most of major complications including a lower incidence of infection and steal syndrome, with patencies at least equivalent to PTFE. There is only a few data in the litterature, but many surgical teams use it when there is no autologous material or in case of infection. The aim of the study is to give the primary patency of vascular access with this technique, and to assess its long term outcomes.

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

End Stage Renal Failure on Dialysis Hemodialysis Access Failure

Interventions

Vascular access by pass using a cold stored venous allograft

Outcomes

Primary Outcomes

Intervention free vascular access survival (in days)

The interval in days between the vascular access creation and the first successful re intervention (primary patency)

Time frame: 30 days

Intervention free vascular access survival (in days)

The interval in days between the vascular access creation and the first successful re intervention (primary patency)

Time frame: 6 months

Intervention free vascular access survival (in days)

The interval in days between the vascular access creation and the first successful re intervention (primary patency)

Time frame: 1 year

Intervention free vascular access survival (in days)

The interval in days between the vascular access creation and the first successful re intervention (primary patency)

Time frame: 2 years

Intervention free vascular access survival (in days)

The interval in days between the vascular access creation and the first successful re intervention (primary patency)

Time frame: 3 years

Secondary Outcomes

Thrombosis free vascular access survival (in days)

The interval in days between the vascular access creation and the first occlusion with a successful re intervention (primary assisted pantency)

Time frame: 30 days

Thrombosis free vascular access survival (in days)

The interval in days between the vascular access creation and the first occlusion with a successful re intervention (primary assisted pantency)

Time frame: 90 days

Thrombosis free vascular access survival (in days)

The interval in days between the vascular access creation and the first occlusion with a successful re intervention (primary assisted pantency)

Time frame: 6 months

Thrombosis free vascular access survival (in days)

The interval in days between the vascular access creation and the first occlusion with a successful re intervention (primary assisted pantency)

Time frame: 1 year

Thrombosis free vascular access survival (in days)

The interval in days between the vascular access creation and the first occlusion with a successful re intervention (primary assisted pantency)

Time frame: 2 years

Thrombosis free vascular access survival (in days)

The interval in days between the vascular access creation and the first occlusion with a successful re intervention (primary assisted pantency)

Time frame: 3 years

Abandonment of the vascular access (in days)