This phase III trial compares telephone delivered Acceptance and Commitment Therapy to standard behavioral therapy for improving weight loss in overweight or obese participants. Acceptance and Commitment Therapy focuses on increasing willingness to experience physical cravings, emotions, and thoughts while making values-guided committed behavior changes. Acceptance and Commitment Therapy may work better at improving weight loss compared to standard behavioral therapy.
OUTLINE: Participants are randomized to 1 of 2 arms. ARM I: Participants receive ACT telephone coaching over the course of 12 months, calls 1-16 weekly, calls 17-23 biweekly, and calls 24-25 monthly. Call 1 is 30 minutes in duration, while calls 2-25 are each 15-20 minutes in duration. ARM II: Participants receive SBT telephone coaching over the course of 12 months, calls 1-16 weekly, calls 17-23 biweekly, and calls 24-25 monthly. Call 1 is 30 minutes in duration, while calls 2-25 are each 15-20 minutes in duration. Participants are followed up at 6, 12, and 24 months after randomization.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
418
Ancillary studies
Receive ACT telephone coaching
Receive SBT telephone coaching
Fred Hutch/University of Washington Cancer Consortium
Seattle, Washington, United States
10% or more weight loss
Will be measured remotely by cellular-enabled scales. Will compare the two telephone interventions, using logistic regression.
Time frame: At 12 months after randomization
Percent weight change
Will be measured remotely by cellular-enabled scales.
Time frame: At 6, 12, and 24-months post randomization
Dietary intake
Will be measured with the Fitbit smartphone app food logging feature.
Time frame: At 6, 12, and 24-months post randomization
Physical activity
Will be measured with the Fitbit Inspire mailed to participants.
Time frame: At 6, 12, and 24-months post randomization
Trajectories of weight change
Will compare between the two arms, with time as the independent variable using mixed effects modeling with linear, quadratic, and cubic effects of time.
Time frame: At 6, 12, and 24-months post randomization
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