ENB Vs. Conventional Bronchoscopy With Fluoroscopy for Safe and Effective Biopsy of Pulmonary Lesions

Inclusion Criteria: * Subjects must meet all of the following criteria to be selected: 1. Be older than 18 (including 18) and younger than 75 (including 75); 2. The population with peripheral lung lesions detected in chest CT scanning and who require biopsy; 3. The subjects are willing to undergo bronchoscopy and meet the requirements for bronchoscopy; 4. The subjects or their guardians can understand the trial objective, volunteer to participate and sign the informed consent form. Exclusion Criteria: * Subjects will be excluded if they meet any of the following criteria: 1. The patient is participating in another drug or medical device clinical trial (drug clinical trial within 3 months or medical device clinical trial within 1 month); 2. Women of childbearing age who have positive pregnancy test result and lactating women; 3. Allergic to anesthetics; 4. Bronchoscopy contraindications, including: active massive hemoptysis; recent myocardial infarction or unstable angina pectoris; severe heart and lung dysfunction; severe hypertension and arrhythmia; uncorrectable bleeding tendency (such as severe coagulation disorders, uremia and severe pulmonary hypertension); severe superior vena cava obstruction syndrome; suspected aortic aneurysm; multiple pulmonary bullae; systemically extreme exhaustion. 5. Visible intraluminal lesions found during bronchoscopy; 6. Patients with severe lung diseases (including: severe bronchodilatation, severe emphysema, etc.) and patients determined to be unsuitable for the examination by the investigators; 7. Patients with a pacemaker or defibrillator; 8. Patients who cannot cooperate with the doctor to complete bronchoscopy, such as patients with mental and neurological diseases, mental retardation and mental disorders; 9. Patients to whom bronchoscopy and bronchoscopic sampling are not applicable to diagnose the lesions, or other patients determined to be unsuitable for this trial by the investigators.