A Clinical Study to Evaluate the Efficacy and Safety of CKD-351

Inclusion Criteria: 1. More than the age of 19 years old 2. Subjects who has primary open-angle glaucoma or ocular hypertension 3. Subjects who sign on an informed consent form willingly Exclusion Criteria: 1. Subjects with intraocular pressure ≥ 35 mmHg at Visit 1 or Visit 2 (AM 09:00) 2. Subjects with a maximum corrected visual acuity ≤ 0.3 in the selected evaluation eye at Visit 1 or Visit 2 3. Subjects who were diagnosed as below * Aphakia * Intraocular lens * Acute or Chronic Closed-Angle Glaucoma * Secondary Glaucoma 4. Subjects with ocular inflammation or infection within the last 3 months 5. Subjects with significant history of ocular trauma during the last 6 months or who underwent surgical opthalmic surgery 6. Subjects who received topical or systemic steroids within the last 1 month.