Study aims to compare the influence of intravenous lidocaine and peridural ropivacaine on postoperative long and short term outcome in patients with pancreatic cancer undergoing surgery. As short term endpoints: postoperative complications and resumption of bowel function. Long term endpoints include: 1 and 3 year recurrence and mortality.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
100
Intraoperatively and postoperatively a standard intravenous infusion of lidocaine will be used for analgesia
Intraoperatively and postoperatively an epidural infusion of ropivacaine will be used for analgesia
Regional Institute of Gastroenterology and Hepatology "Prof. Dr. O. Fodor"
Cluj-Napoca, Romania
1- and 3-years recurrence rate after surgery
Study participants will be contacted by study team via phone or e-mail
Time frame: 3 years
1- and 3-years survival after surgery
Study participants will be contacted by study team via phone or e-mail
Time frame: 3 years
Lidocaine and ropivacaine concentration
Time frame: Intraoperatively
Complication rate after surgery
Resumption of bowel function, anastomotic leakage or hemorrhage
Time frame: 2 weeks
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