In Pakistan, breastfeeding is widely practiced. National data suggests that 94% of infants \<2 years of age receive breastmilk at some point. However, the introduction of complementary foods often occurs early. At 3 months of age, it is suggested that only 54% of Pakistani infants are exclusively breastfed. This declines with each month of age. Because the production and release of breastmilk is influenced by the frequency and intensity of suckling, early initiation of complementary feeding can reduce breastmilk output. Given that complementary foods are introduced early within Pakistan, we hypothesize that breastmilk composition will change between 1 and 3 months postpartum among those mother-infant pairs if nutritive complementary foods are introduced early (i.e., before 6 months). In this study, we aim to better understand how breastmilk composition changes over time among infants recruited at 1 month of age who are exclusively breastfed or receive only non-nutritive feeds. This is a substudy to the Matiari emPowerment and Preconception Supplementation (MaPPS) Trial (ClinicalTrials.gov Identifier: NCT03287882).
Study Type
OBSERVATIONAL
Enrollment
50
No intervention
Matiari Research and Training Centre
Matiari, Sindh, Pakistan
Change in breastmilk macronutrient composition
Time frame: 1 and 3 months postpartum
Change in breastmilk micronutrient composition
Time frame: 1 and 3 months postpartum
Change in breastmilk bioactive composition
Time frame: 1 and 3 months postpartum
Change in breastmilk microbiome
Time frame: 1 and 3 months postpartum
Change in infant microbiome
Time frame: 1 and 3 months postpartum
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