Parkinson' patients who have not had dyskinesia would be observed for 2 years in a multicenter prospective study with the purposes to clarify the predicting factors of dyskinesia.
Parkinson' patients with daily levodopa dosage above 200mg and no dyskinesia would be recruited into the study. They would be observed for two years for analyzed the predicting factors of dyskinesia. At the baseline, demographic information, Clinical information, blood sample, picture of tongure coating would be collected at the baseline. All participants were evaluated every three months for two years. The severity of motor symptoms were evaluated every 6 months.
Study Type
OBSERVATIONAL
Enrollment
300
Xinhua hospital affiliated to Shanghai jiaotong university school of medicine
Shanghai, Shanghai Municipality, China
the occurrence of dyskinesia and its related predicting factors
to evaluate the occurrence of dyskinesia during the 2 years of follow-up and identify its predicting factors of dyskinesia
Time frame: The data would be analyzed within 9 months of the study completion. The outcome would be reported within 1 year of the the study completion.
to evaluate patients ' living quality and the severity of non motor symptoms during the 2 years of follow-up
to evaluate patients ' living quality and the severity of non motor symptoms during the 2 years of follow-up
Time frame: The data would be analyzed within 9 months of the study completion. The outcome would be reported within 1 year of the the study completion.
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